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The Next Generation in Hot Start PCR

Novel Technology

CleanAmp™ Primers contain thermolabile chemical modifications that allow for primer-based “hot start” activation in PCR. These modifications prevent primer extension at the lower temperatures of PCR set-up and manipulation. A “hot start” thermal activation step removes the modification and generates the corresponding unmodified primer, which supports amplification of the undesired target.
More About CleanAmp™ Primer Technology>>

Which CleanAmp™ Primer is right for my application?

CleanAmp™ Primers are available in two forms, which vary in the rate of thermal activation.  CleanAmp™ Turbo II modifications are released more quickly than those for CleanAmp™ Precision II. The two different speeds of primer activation are suited for a number of PCR-based applications.

CleanAmp™ Turbo II Primers


CleanAmp™ Precision II Primers
  • Fast cycling (<45 min. total cycling time)
  • Standard cycling (>45 min. total cycling time)
  • Multiplexed PCR
  • Reverse-transcription PCR
  • Improved amplicon yield
  • Improved specificity and limit of detection
  • Reduced mis-priming/primer dimer formation
  • Greatest reduction in mis-priming/primer dimer formation
Technical Resources  
R&D Poster- September 2008 MSDS
R&D Poster- April 2008 Product Brochure
Product Manual ResearchRewards
CleanAmp™ Primer FAQs Join our mailing list!
 
Application Notes  
General CleanAmp™ Application Note
Multiplex PCR CleanAmp™ Application Note
One-Step RT-PCR CleanAmp™ Primer Application Note
Fast Cycling PCR CleanAmp™ Primer Application Note
   

CleanAmp™ is a trademark of TriLink BioTechnologies, Inc.  This product or portions thereof is covered by TriLink pending Patent Applications, US2007281308 and  WO2007139723, and US Patent 6762298 licensed from the Department of Health and Human Services.  CleanAmp™ products are sold exclusively for R & D use by the purchaser.  They may not be used for clinical or diagnostic purposes and they may not be resold, distributed or re-packaged.  No license is granted or implied with the purchase of this product.  It may be necessary to obtain a license for certain patented applications in which the product is used.
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